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These results were positively reflected in the BCM-95 group’s serum inflammatory markers: CRP levels were reduced by 37.21%, and TNF-α levels were cut by 74.81%, indicating BCM-95 performed better than paracetamol.
Led by Shuba Singhal, PhD, this randomized, controlled clinical study was conducted at the Department of Orthopedics of Lok Nayak Jai Prakash Hospital/Maulana Azad Medical College, New Delhi. For the study, 193 patients diagnosed with osteoarthritis of the knee were randomized to receive either turmeric extract (BCM-95) as a 500 mg capsule two times daily, or a 650 mg tablet of paracetamol three times daily for six weeks.
“The goal of the current study was to build on the earlier studies to give a better clarity and specificity by including more markers and a better scoring methodology,” said Benny Antony, joint managing director for Arjuna. “The anti-arthritic effect of BCM-95 in osteoarthritis is attributed to its capability to modulate anti-inflammatory markers TNF and CRP.”
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These results were positively reflected in the BCM-95 group’s serum inflammatory markers: CRP levels were reduced by 37.21%, and TNF-α levels were cut by 74.81%, indicating BCM-95 performed better than paracetamol.
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Previous CISA guidance broadly protected many of these industries under more imprecise food or health related categories, so the added specificity was welcome for companies in the industries named.
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There are two main types of immune system response: innate immunity and adaptive immunity. Innate immunity refers to our body’s first line of defence against pathogens whose main purpose is to immediately prevent the spread of said pathogens across the body. Adaptive immunity would be the second line of defence in the fight against non-self pathogens.
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Exhibition area: 20000+ square meters
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Started with the 'Microencapsulation series products’ and with the detailed introduction of latest product trend, such as the Lycopene CWS/beadlets, Astaxanthin CWS/beadlets, 5-HTP, Melatonin, etc., we Finutra biotech looking forward to contribute to the botanical extract industry by our efforts.
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“We are learning more about the mechanisms behind curcumin’s anti-inflammatory effect which we believe is a result of its ability to inhibit pro-inflammatory signals, such as prostaglandins, leukotrienes, and cyclooxygenase-2. In addition, curcumin has been demonstrated to suppress several pro-inflammatory cytokines and mediators of their release, such as tumor necrosis factor-α (TNF-α), IL-1, IL-8, and nitric oxide synthase,”said Antony.
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