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Knee OA is the leading cause of disability and pain among adult and old age populations. An estimated 10 to 15% of all adults older than 60 years have some degree of OA, with prevalence higher among women than men.

“We found that 1-week supplementation with tomato powder positively augmented total antioxidant capacity and was more potent when compared to lycopene supplementation,” the authors of the study said. “These trends in 8-isoprostane and MDA support the notion that over a short period of time, tomato powder, not synthetic lycopene, has the potential to alleviate exercise-induced lipid peroxidation. MDA is a biomarker of oxidation of total lipid pools but 8-isoprostane belongs to F2-isoprostane class and is a reliable biomarker of radical-induced reaction which specifically reflects the oxidation of arachidonic acid.”

Osteoarthritis is a degenerative disease of the articular joints characterized by the breakdown of cartilage, joint lining, ligaments, and underlying bone. Common manifestations of osteoarthritis are stiffness and pain.

Based on the results of the study, the authors concluded that the significantly greater benefits tomato powder had on antioxidant capacity and exercise-induced peroxidation may have been brought on by a synergistic interaction between lycopene and other bioactive nutrients, rather than from lycopene in an isolated format.

Among the popular nutritional supplements used to optimize exercise recovery by athletes, lycopene, a carotenoid found in tomatoes, is widely used, with clinical research evidencing that pure lycopene supplements are a potent antioxidant which can reduce exercise-induced lipid peroxidation (a mechanism in which free radicals damage cells by “stealing” electrons from lipids in cell membranes).

Astaxanthin is a unique fat-soluble antioxidant carotenoid found in algae, yeast, salmon, krill, shrimp and other kinds of fish and crustaceans. Clinical trials indicate that astaxanthin improve the condition of the skin, enhance recovery from exercise, relieve occasional indigestion, support gastric health, help maintain cholesterol level within a healthy range, enhance immune response, promote healthy vision, and support the male reproductive system.