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In the randomized, double-blinded crossover study, 11 well-trained male athletes underwent three exhaustive exercise tests after a week of supplementation with a tomato powder, then a lycopene supplement, and then a placebo. Three blood samples (baseline, post-ingestion, and post-exercise) were taken for each of the supplements used, in order to evaluate total antioxidant capacity and variables of lipid peroxidation, such as malondialdehyde (MDA) and 8-isoprostane.
Led by Shuba Singhal, PhD, this randomized, controlled clinical study was conducted at the Department of Orthopedics of Lok Nayak Jai Prakash Hospital/Maulana Azad Medical College, New Delhi. For the study, 193 patients diagnosed with osteoarthritis of the knee were randomized to receive either turmeric extract (BCM-95) as a 500 mg capsule two times daily, or a 650 mg tablet of paracetamol three times daily for six weeks.
“We found that 1-week supplementation with tomato powder positively augmented total antioxidant capacity and was more potent when compared to lycopene supplementation,” the authors of the study said. “These trends in 8-isoprostane and MDA support the notion that over a short period of time, tomato powder, not synthetic lycopene, has the potential to alleviate exercise-induced lipid peroxidation. MDA is a biomarker of oxidation of total lipid pools but 8-isoprostane belongs to F2-isoprostane class and is a reliable biomarker of radical-induced reaction which specifically reflects the oxidation of arachidonic acid.”
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CPhI Shanghai 2023 is not just a networking event but also a platform for knowledge sharing and staying up-to-date with the latest trends and developments in the industry. We look forward to attending various informative sessions, participating in engaging discussions, and gaining new perspectives from esteemed industry leaders.
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“Most of our member companies wanted to stay open, and were staying open under the assumption that they were a part of either the food sector or the health care sector,” said Steve Mister, president and CEO of the Council for Responsible Nutrition (CRN), in an interview. “What this does is it makes it clear. So if someone from state law enforcement should show up and ask, 'Why are you open?’ they can directly point to the CISA guidance.”
Mister added, “When the first round of this memo came out, we were pretty confident that we would be included by inference … but it didn’t expressly say dietary supplements. You kind of had to read between the lines to read us into it.” - 9ashwagandha root and leaf extract
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