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“We found that 1-week supplementation with tomato powder positively augmented total antioxidant capacity and was more potent when compared to lycopene supplementation,” the authors of the study said. “These trends in 8-isoprostane and MDA support the notion that over a short period of time, tomato powder, not synthetic lycopene, has the potential to alleviate exercise-induced lipid peroxidation. MDA is a biomarker of oxidation of total lipid pools but 8-isoprostane belongs to F2-isoprostane class and is a reliable biomarker of radical-induced reaction which specifically reflects the oxidation of arachidonic acid.”

“We are learning more about the mechanisms behind curcumin’s anti-inflammatory effect which we believe is a result of its ability to inhibit pro-inflammatory signals, such as prostaglandins, leukotrienes, and cyclooxygenase-2. In addition, curcumin has been demonstrated to suppress several pro-inflammatory cytokines and mediators of their release, such as tumor necrosis factor-α (TNF-α), IL-1, IL-8, and nitric oxide synthase,”said Antony.

BCM-95’s unique fusion of curcuminoids and turmerone-rich essential oil components overcomes curcumin’s characteristic bioavailability hurdles due to its inherent high lipophilic nature.

In a new pilot study, published in the Journal of the International Society of Sports Nutrition, researchers aimed to investigate the antioxidant benefits of lycopene, but specifically, how they stacked up against tomato powder, a tomato supplement closer to its whole food origin which contains not only lycopene but a broader profile of micronutrients and various bioactive components.

Led by Shuba Singhal, PhD, this randomized, controlled clinical study was conducted at the Department of Orthopedics of Lok Nayak Jai Prakash Hospital/Maulana Azad Medical College, New Delhi. For the study, 193 patients diagnosed with osteoarthritis of the knee were randomized to receive either turmeric extract (BCM-95) as a 500 mg capsule two times daily, or a 650 mg tablet of paracetamol three times daily for six weeks.