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Knee arthritis symptoms of pain, joint stiffness, and diminished physical function were evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). After six weeks of treatment, responder analysis showed significant improvement in WOMAC scores across all parameters comparable to the paracetamol group, with 18% of the BCM-95 group reporting 50% improvement, and 3% of subjects noting 70% improvement.

“The goal of the current study was to build on the earlier studies to give a better clarity and specificity by including more markers and a better scoring methodology,” said Benny Antony, joint managing director for Arjuna. “The anti-arthritic effect of BCM-95 in osteoarthritis is attributed to its capability to modulate anti-inflammatory markers TNF and CRP.”

Based on the results of the study, the authors concluded that the significantly greater benefits tomato powder had on antioxidant capacity and exercise-induced peroxidation may have been brought on by a synergistic interaction between lycopene and other bioactive nutrients, rather than from lycopene in an isolated format.

Astaxanthin is a unique fat-soluble antioxidant carotenoid found in algae, yeast, salmon, krill, shrimp and other kinds of fish and crustaceans. Clinical trials indicate that astaxanthin improve the condition of the skin, enhance recovery from exercise, relieve occasional indigestion, support gastric health, help maintain cholesterol level within a healthy range, enhance immune response, promote healthy vision, and support the male reproductive system.