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Knee OA is the leading cause of disability and pain among adult and old age populations. An estimated 10 to 15% of all adults older than 60 years have some degree of OA, with prevalence higher among women than men.

The nutraceutical supplement market has experienced significant growth in recent years, driven by the increasing interest in maintaining a healthy lifestyle. Nutraceutical supplements are designed to provide nutritional benefits, and they are becoming increasingly popular as more people become aware of their benefits.

Coronavirus has dramatically increased U.S. consumer demand in many dietary supplements, whether it is for improved nutrition during the crisis, assistance with sleep and stress relief, or supporting a strong immune function to improve general resistance to health threats.