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In the randomized, double-blinded crossover study, 11 well-trained male athletes underwent three exhaustive exercise tests after a week of supplementation with a tomato powder, then a lycopene supplement, and then a placebo. Three blood samples (baseline, post-ingestion, and post-exercise) were taken for each of the supplements used, in order to evaluate total antioxidant capacity and variables of lipid peroxidation, such as malondialdehyde (MDA) and 8-isoprostane.

Knee arthritis symptoms of pain, joint stiffness, and diminished physical function were evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). After six weeks of treatment, responder analysis showed significant improvement in WOMAC scores across all parameters comparable to the paracetamol group, with 18% of the BCM-95 group reporting 50% improvement, and 3% of subjects noting 70% improvement.

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Among the popular nutritional supplements used to optimize exercise recovery by athletes, lycopene, a carotenoid found in tomatoes, is widely used, with clinical research evidencing that pure lycopene supplements are a potent antioxidant which can reduce exercise-induced lipid peroxidation (a mechanism in which free radicals damage cells by “stealing” electrons from lipids in cell membranes).

Makers of dietary supplements specifically were mentioned in the context of health care or public health companies, and listed with other industries like biotechnology, distributors of medical equipment, personal protective equipment, pharmaceuticals, vaccines, even tissue and paper towel products.

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