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In the randomized, double-blinded crossover study, 11 well-trained male athletes underwent three exhaustive exercise tests after a week of supplementation with a tomato powder, then a lycopene supplement, and then a placebo. Three blood samples (baseline, post-ingestion, and post-exercise) were taken for each of the supplements used, in order to evaluate total antioxidant capacity and variables of lipid peroxidation, such as malondialdehyde (MDA) and 8-isoprostane.

Based on the results of the study, the authors concluded that the significantly greater benefits tomato powder had on antioxidant capacity and exercise-induced peroxidation may have been brought on by a synergistic interaction between lycopene and other bioactive nutrients, rather than from lycopene in an isolated format.