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Knee OA is the leading cause of disability and pain among adult and old age populations. An estimated 10 to 15% of all adults older than 60 years have some degree of OA, with prevalence higher among women than men.

Makers of dietary supplements specifically were mentioned in the context of health care or public health companies, and listed with other industries like biotechnology, distributors of medical equipment, personal protective equipment, pharmaceuticals, vaccines, even tissue and paper towel products.