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Knee arthritis symptoms of pain, joint stiffness, and diminished physical function were evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). After six weeks of treatment, responder analysis showed significant improvement in WOMAC scores across all parameters comparable to the paracetamol group, with 18% of the BCM-95 group reporting 50% improvement, and 3% of subjects noting 70% improvement.

Given the current demand for alternative sources of foods with suitable functional characteristics, the adaptogen effect could be an interesting attribute to consider in determining the use of certain plants in the formulation of foods and beverages.

Based on the results of the study, the authors concluded that the significantly greater benefits tomato powder had on antioxidant capacity and exercise-induced peroxidation may have been brought on by a synergistic interaction between lycopene and other bioactive nutrients, rather than from lycopene in an isolated format.

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“We are learning more about the mechanisms behind curcumin’s anti-inflammatory effect which we believe is a result of its ability to inhibit pro-inflammatory signals, such as prostaglandins, leukotrienes, and cyclooxygenase-2. In addition, curcumin has been demonstrated to suppress several pro-inflammatory cytokines and mediators of their release, such as tumor necrosis factor-α (TNF-α), IL-1, IL-8, and nitric oxide synthase,”said Antony.

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