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Knee arthritis symptoms of pain, joint stiffness, and diminished physical function were evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). After six weeks of treatment, responder analysis showed significant improvement in WOMAC scores across all parameters comparable to the paracetamol group, with 18% of the BCM-95 group reporting 50% improvement, and 3% of subjects noting 70% improvement.

With the brevity of the study duration, the authors did hypothesize, however, that a longer-term supplementation regimen of lycopene could result in stronger antioxidant benefits for the isolated nutrient, in accordance with other studies that were carried out over a period of several weeks. Nonetheless, whole tomato contains chemical compounds that can enhance beneficial outcomes in synergy compared to a single compound, the authors said.