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Knee arthritis symptoms of pain, joint stiffness, and diminished physical function were evaluated using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). After six weeks of treatment, responder analysis showed significant improvement in WOMAC scores across all parameters comparable to the paracetamol group, with 18% of the BCM-95 group reporting 50% improvement, and 3% of subjects noting 70% improvement.

Based on the results of the study, the authors concluded that the significantly greater benefits tomato powder had on antioxidant capacity and exercise-induced peroxidation may have been brought on by a synergistic interaction between lycopene and other bioactive nutrients, rather than from lycopene in an isolated format.

Osteoarthritis is a degenerative disease of the articular joints characterized by the breakdown of cartilage, joint lining, ligaments, and underlying bone. Common manifestations of osteoarthritis are stiffness and pain.