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Knee OA is the leading cause of disability and pain among adult and old age populations. An estimated 10 to 15% of all adults older than 60 years have some degree of OA, with prevalence higher among women than men.

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“We are learning more about the mechanisms behind curcumin’s anti-inflammatory effect which we believe is a result of its ability to inhibit pro-inflammatory signals, such as prostaglandins, leukotrienes, and cyclooxygenase-2. In addition, curcumin has been demonstrated to suppress several pro-inflammatory cytokines and mediators of their release, such as tumor necrosis factor-α (TNF-α), IL-1, IL-8, and nitric oxide synthase,”said Antony.

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In a new pilot study, published in the Journal of the International Society of Sports Nutrition, researchers aimed to investigate the antioxidant benefits of lycopene, but specifically, how they stacked up against tomato powder, a tomato supplement closer to its whole food origin which contains not only lycopene but a broader profile of micronutrients and various bioactive components.

 

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