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With the brevity of the study duration, the authors did hypothesize, however, that a longer-term supplementation regimen of lycopene could result in stronger antioxidant benefits for the isolated nutrient, in accordance with other studies that were carried out over a period of several weeks. Nonetheless, whole tomato contains chemical compounds that can enhance beneficial outcomes in synergy compared to a single compound, the authors said.

“The goal of the current study was to build on the earlier studies to give a better clarity and specificity by including more markers and a better scoring methodology,” said Benny Antony, joint managing director for Arjuna. “The anti-arthritic effect of BCM-95 in osteoarthritis is attributed to its capability to modulate anti-inflammatory markers TNF and CRP.”

In the athletes, tomato powder enhanced total antioxidant capacity by 12%. Interestingly, the tomato powder treatment also resulted in a significantly reduced elevation of 8-isoprostane compared to both the lycopene supplement and the placebo. The tomato powder also significantly reduced exhaustive exercise MDA compared to the placebo, however, no such difference was indicated between the lycopene and placebo treatments.