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These results were positively reflected in the BCM-95 group’s serum inflammatory markers: CRP levels were reduced by 37.21%, and TNF-α levels were cut by 74.81%, indicating BCM-95 performed better than paracetamol.

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With the brevity of the study duration, the authors did hypothesize, however, that a longer-term supplementation regimen of lycopene could result in stronger antioxidant benefits for the isolated nutrient, in accordance with other studies that were carried out over a period of several weeks. Nonetheless, whole tomato contains chemical compounds that can enhance beneficial outcomes in synergy compared to a single compound, the authors said.

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“The goal of the current study was to build on the earlier studies to give a better clarity and specificity by including more markers and a better scoring methodology,” said Benny Antony, joint managing director for Arjuna. “The anti-arthritic effect of BCM-95 in osteoarthritis is attributed to its capability to modulate anti-inflammatory markers TNF and CRP.”

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